3-Piperidinecarboxylic acid, 1-(2-pyridinyl)-

3-Piperidinecarboxylic acid, 1-(2-pyridinyl)- - Names and Identifiers

Name	3,4,5,6-Tetrahydro-2H-[1,2']bipyridinyl-3-carboxylic acid
Synonyms	TIMTEC-BB SBB011141 1-Pyridin-2-ylpiperidine-3-carboxylic acid 1-(2-Pyridinyl)-3-piperidinecarboxylic acid 3-Piperidinecarboxylic acid, 1-(2-pyridinyl)- 3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRIDINYL-3-CARBOXYLIC ACID 3,4,5,6-Tetrahydro-2H-[1,2']bipyridinyl-3-carboxylic acid
CAS	876718-04-6
InChI	InChI=1S/C11H14N2O2/c14-11(15)9-4-3-7-13(8-9)10-5-1-2-6-12-10/h1-2,5-6,9H,3-4,7-8H2,(H,14,15)

3-Piperidinecarboxylic acid, 1-(2-pyridinyl)- - Physico-chemical Properties

Molecular Formula	C11H14N2O2
Molar Mass	206.24
Density	1.233 g/cm3
Boling Point	407.9 °C at 760 mmHg
Flash Point	200.5 °C
Storage Condition	2-8°C

3-Piperidinecarboxylic acid, 1-(2-pyridinyl)- - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT

3-Piperidinecarboxylic acid, 1-(2-pyridinyl)- - Introduction

3,4,5,6-Tetrahydro-2H-[1,2 ']bipyridinyl-3-carboxylic acid is an organic compound with the chemical formula C12H16N2O2. It has the following properties:

Nature:
-Appearance: White crystalline solid
-Solubility: Soluble in common organic solvents such as ethanol and dichloromethane
-Melting point: about 150-152°C

Use:
-As an intermediate in organic synthesis, it can be used to synthesize drugs and other compounds
-Catalysts that can be used in coordination chemistry and catalytic reactions

Preparation Method:
The preparation method of 3,4,5,6-Tetrahydro-2H-[1,2 ']bipyridinyl-3-carboxylic acid can be carried out by the following steps:
1. to nitrosobenzoic acid salt as raw material, under alkaline conditions with acetylene reaction, the generation of 2-amino phenyl acetylene acid salt.
2. 2-Aminophenylacetylethynate is reacted with p-formaldehyde, and 4-aminobutanol compound is obtained by alcoholation reaction against a pyridine bicyclic ring.
3. Finally, the 4-aminobutanol compound is subjected to an acylation reaction under appropriate reaction conditions to form the final product 3,4,5,6-Tetrahydro-2H-[1,2 ']bipyridinyl-3-carboxylic acid.

Safety Information: The specific safety and toxicity of
3,4,5,6-Tetrahydro-2H-[1,2 ']bipyridinyl-3-carboxylic acid requires further testing and evaluation. Appropriate safety measures, such as wearing gloves, protective glasses and protective clothing, are required when handling the compound. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. At the same time, the compound should be stored in a dry, cool place, and away from fire and oxidizing agents. Observe local safety regulations and proper operating procedures when using and disposing of the compound.

Last Update：2024-04-09 21:11:58